In eukaryotes, the initiator tRNA for translation is....
a) Met-tRNAfMet, which is also used by archaea and bacteria
b) Met-tRNAfMet, which is also used by archaea
c) different from the initiator used by bacteria and archaea
d) fMet-tRNAfMet, which is also used by bacteria
Answer
c) different from the initiator used by bacteria and
archaea
- tRNA is used in the initiation step of protein synthesis.
- the initiator tRNA in eukaryotes is Met-tRNA (i.e.
methionine) - in prokaryotes initial tRNA is formylated by methionyl
tRNA transformylase (Met-tRNA f) - in bacterial tRNA Watson–Crick base pair is absent between
positions 1 and 72 in acceptor stem - initiator tRNA in eukaryotes are represenred with the presence
of a particular A1:U72 Watson–Crick base pair in the acceptor
stem