Why are changes in nucleosome spacing important in changing gene expression?

Why are changes in nucleosome spacing important in changing gene
expression?

Select the two correct answers.

Select the two correct answers.

When DNA is unmethylated and histones are acetylated,
nucleosomes are spaced in the open configuration and transcription
can occur.
When DNA is methylated and histones are deacetylated,
nucleosomes are relatively close together and transcription is
suppressed.
Nucleosome spacing depends on maternal and paternal imprinting
and influences organismal adaptability to environmental
stress.
When DNA is phosphorylated or methylated and histones are
acetylated, transcriptional activity is stimulated at specific DNA
regions.

Answer

Changes in nucleosome spacing important in changing gene
expression

The correct two statements are below

When DNA is methylated and histones are deacetylated,
nucleosomes are relatively close together and transcription is
suppressed.

When DNA is unmethylated and histones are acetylated,
nucleosomes are spaced in the open configuration and transcription
can occur.

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